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Assays & Technologies

Chemistry Platform

Compound solubility test [Code No: IPK1101]

The solubility test procedure is based on attempting to dissolve chemicals in various solvents. High-throughput solubility assays in discovery are often kinetic solubility assays that are based on the detection of precipitation of compounds in aqueous solutions. The resulting precipitation is detected optically, and the kinetic solubility is defined as the concentration preceding the point at which precipitation occurs.

Compound synthesis [Code No: IPK1102]

This includes: chemical synthesis of compounds in small to medium scale; synthesis of nucleosides, peptides and natural products; synthesis of assay development tools and reagents; synthesis of cold-labeled (C13, H2, N15) compounds; purification of active materials from extracts; structure determination; and performing structure-activity relationship (SAR) studies.