알림·소식
알림·소식
[2019 Pasteur Colloquium] 김창진 박사, 한국생명공학연구원
2019-07-08
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[한국파스퇴르연구소] 파스퇴르 콜로퀴엄
일시 : 2019년 7월 11일 (목), 오전 11시
장소 : 모노드 회의실 (1층), 한국파스퇴르연구소
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연자
김창진 박사
한국생명공학연구원 산업바이오소재연구센터 책임연구원
강연주제
Exploitation of chemical diversity from microbial diversity for the
discovery of useful biomaterials
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*파스퇴르 콜로퀴엄 관련 문의사항은 sukyon.yang@ip-korea.org 로 이메일 송부 부탁드립니다. 연구소 관련 추가 내용은 홈페이지 (www.ip-korea.org) 를 통해 확인하실 수 있습니다.
** 한국파스퇴르연구소 약도: http://www.ip-korea.org/about_us/location.php
[한국파스퇴르연구소] 파스퇴르 콜로퀴엄
일시 : 2019년 7월 11일 (목), 오전 11시
장소 : 모노드 회의실 (1층), 한국파스퇴르연구소
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연자김창진 박사
한국생명공학연구원 산업바이오소재연구센터 책임연구원
강연주제
Exploitation of chemical diversity from microbial diversity for the
discovery of useful biomaterials
초록
Microbial genetic resources are very important and useful for screening of bioactivities. Only less than 1% of living bacterial species and 5% of fungal species have been cultured, so a lot of them are untapped yet. Adopting selective isolation and de-replication techniques for exploiting new, neglected, rare species will also extend the microbial library as efficient screening sources. Microorganisms produce various kinds of metabolites from a chemical diversity point of view. Screening of new types of biomaterials of microbial origin is a meaningful solution for discovery program. Therefore, Mining microbial metabolites of small molecules for screening strategy is still very promising!
We have tried to get good quality microbial library including some new species and extremophiles for many decades. Tthe total microbial number of strains which we have comes up to over twenty thousands - about 60% of those are actinomycetes. We have kept and provide these isolated strains and culture broth or solvent extracts as screening resources. A value evaluation project (http://www.mrscc.net) is under way on this microbial resources which we have secured for twenty years. This is covering the cultural characteristics and the information on identification and some bioactivities, not just the strains we have. Among them, many strains or culture extracts were provided to related industry, institute and academia for their effective screening research with a lot of information database. Introduction to our microbial resources and some achievement of biomaterial discovery will be introduced and discussed.Microbial genetic resources are very important and useful for screening of bioactivities. Only less than 1% of living bacterial species and 5% of fungal species have been cultured, so a lot of them are untapped yet. Adopting selective isolation and de-replication techniques for exploiting new, neglected, rare species will also extend the microbial library as efficient screening sources. Microorganisms produce various kinds of metabolites from a chemical diversity point of view. Screening of new types of biomaterials of microbial origin is a meaningful solution for discovery program. Therefore, Mining microbial metabolites of small molecules for screening strategy is still very promising!
___________________________________________
*파스퇴르 콜로퀴엄 관련 문의사항은 sukyon.yang@ip-korea.org 로 이메일 송부 부탁드립니다. 연구소 관련 추가 내용은 홈페이지 (www.ip-korea.org) 를 통해 확인하실 수 있습니다.
** 한국파스퇴르연구소 약도: http://www.ip-korea.org/about_us/location.php