Lead optimization of a novel series of imidazo[1,2-a]pyridine amides leading to a clinical candidate (Q203) as a multi- and extensively-drug-resistant anti-tuberculosis agent.

Kang S, Kim RY, Seo MJ, Lee S, Kim YM, Seo M, Seo JJ, Ko Y, Choi I, Jang J, Nam J, Park S, Kang H, Kim HJ, Kim J, Ahn S, Pethe...

In vitro antiplasmodial activities and synergistic combinations of differential solvent extracts of the polyherbal product, Nefang.

Arrey Tarkang P, Franzoi KD, Lee S, Lee E, Vivarelli D, Freitas-Junior L, Liuzzi M, Nole T, Ayong LS, Agbor GA, Okalebo FA, Gua...

A 1536-well fluorescence polarization assay to screen for modulators of the MUSHASHI family of RNA-binding proteins

Minuesa G, Antczak C, Shum D, Radu C, Bhinder B, Li Y, Djaballah H, Kharas MG

Plasmid-based shRNA lentiviral particle production for RNAi applications

Shum D, Djaballah H

Mycobacterial toxin induces analgesia in buruli ulcer by targeting the angiotensin pathways.

Marion E, Song OR, Christophe T, Babonneau J, Fenistein D, Eyer J, Letournel F, Henrion D, Clere N, Paille V, Guerineau NC, Sai...

Secondary metabolites from Vietnamese marine invertebrates with activity against Trypanosoma brucei and T. cruzi.

Thao NP, No JH, Luyen BT, Yang G, Byun SY, Goo J, Kim KT, Cuong NX, Nam NH, Van Minh C, Schmidt TJ, Kang JS, Kim YH.

Discovery of a dicer-independent, cell-type dependent alternate targeting sequence generator: implications in gene silencing & pooled RNAi screens

Bhinder B, Shum D, Li M, Ibanez G, Vlassov AV, Magdaleno S, Djaballah H

Synthesis and biological evaluation of 2,3-dihydroimidazo[1,2-a]benzimidazole derivatives against Leishmania donovani and Trypanosoma cruzi.

Oh S, Kim S, Kong S, Yang G, Lee N, Han D, Goo J, Siqueira-Neto JL, Freitas-Junior LH, Song R.

Kinome siRNA screen identifies novel cell-type specific dengue host target genes.

Kwon YJ, Heo J, Wong HE, Cruz DJ, Velumani S, da Silva CT, Mosimann AL, Duarte Dos Santos CN, Freitas-Junior LH, Fink K.

Regulation of the hepatitis C virus RNA replicase by endogenous lipid peroxidation.

Yamane D, McGivern DR, Wauthier E, Yi M, Madden VJ, Welsch C, Antes I, Wen Y, Chugh PE, McGee CE, Widman DG, Misumi I, Bandyopa...