Quantification of protein interaction in living cells by two-photon spectral imaging with fluorescent protein fluorescence resonance energy transfer pair devoid of acceptor bleed-through.

Kim J, Li X, Kang MS, Im KB, Genovesio A, Grailhe R.

A high-content subtractive screen for selecting small molecules affecting internalization of GPCRs.

Kwon YJ, Lee W, Genovesio A, Emans N.

Ethionamide boosters. 2. Combining bioisosteric replacement and structure-based drug design to solve pharmacokinetic issues in a series of potent 1,2,4-oxadiazole EthR inhibitors.

Flipo M, Desroses M, Lecat-Guillet N, Villemagne B, Blondiaux N, Leroux F, Piveteau C, Mathys V, Flament MP, Siepmann J, Viller...

A novel specific edge effect correction method for RNA interference screenings.

Carralot JP, Ogier A, Boese A, Genovesio A, Brodin P, Sommer P, Dorval T.

A high-throughput scintillation proximity-based assay for human DNA ligase IV

Tseng HM, Shum D, Bhinder B, Escobar S, Veomett NJ, Tomkinson AE, Gin DY, Djaballah H, Scheinberg DA

Emerging cellular targets for influenza antiviral agents.

Muller KH, Kakkola L, Nagaraj AS, Cheltsov AV, Anastasina M, Kainov DE.

Ketoamide resistance and hepatitis C virus fitness in Val55 variants of the NS3 serine protease.

Welsch C, Schweizer S, Shimakami T, Domingues FS, Kim S, Lemon SM, Antes I.

A high throughput scintillation proximity imaging assay for protein methyltransferases

Ibanez G, Shum D, Blum G, Bhinder B, Radu C, Antczak C, Luo M, Djaballah H

Discovery of 3,4-dihydropyrimidin-2(1H)-ones with inhibitory activity against HIV-1 replication.

Kim J, Park C, Ok T, So W, Jo M, Seo M, Kim Y, Sohn JH, Park Y, Ju MK, Kim J, Han SJ, Kim TH, Cechetto J, Nam J, Sommer P, No Z.

High content screening for compounds that induce early stages of human embryonic stem cell differentiation.

Jee J, Jeon H, Hwang D, Sommer P, Park Z, Cechetto J, Dorval T.