Viral Immunology Lab. We aim to understand immunological principles underlying response to viral infections and vaccinations in an effort to develop interventions for immune-associated diseases including infectious diseases and cancer. Zoonotic Virus Lab. We study emerging viruses, focusing on coronaviruses, mosquito-borne flaviviruses (e.g., dengue and Zika viruses), and tick-borne bunyavirus (e.g., SFTS virus). Our ultimate goal is to understand the biology of these viruses and to develop therapeutic interventions (e.g. small molecule inhibitors and therapeutic antibodies). Antibacterial Resistance Lab. Antibiotic resistance is a global public health threat estimated to risk a mortality rate of over 10 million people a year by 2050. We aim to discover new antibacterial agents and targets by understanding bacterial physiology and fundamental mechanisms of antibiotic resistance. Advanced Biomedical Research Lab. Our goal is to develop drugs to treat Hepatocellular carcinoma (HCC) and liver cirrhosis. We aim to think outside of the box by developing physiologically relevant assay systems recapitulating the tumor microenvironment and enhancing the early drug discovery pipeline converging to HCC therapeutics.